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Beilstein J. Org. Chem. 2015, 11, 1235–1240, doi:10.3762/bjoc.11.137
Graphical Abstract
Figure 1: General template for heterocycle-fused 1,4-naphthoquinones.
Scheme 1: Methods for the preparation of hexahydropyrimidine-fused 1,4-naphthoquinones.
Scheme 2: Synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones 13 and 21–25.
Figure 2: ORTEP diagram of compound 18 depicted with ellipsoids drawn at the 50% probability level and the at...
Figure 3: ORTEP diagram of compound 23 depicted with ellipsoids drawn at the 50% probability level and the at...
Scheme 3: Proposed mechanism for the formation of 13 and 21–25.